With a chain drive transmission, a chainring attached to a crank drives the chain, which in turn rotates the rear wheel via the rear sprocket(s) (cassette or freewheel). There are four gearing options: two-speed hub gear integrated with chain ring, up to 3 chain rings, up to 11 sprockets, hub gear built into rear wheel (3-speed to 14-speed). The most common options are either a rear hub or multiple chain rings combined with multiple sprockets (other combinations of options are possible but less common).
There are individuals who claim to have lost considerable amounts of weight by using an electric bike. A recent prospective cohort study however found that people using e-bikes have a higher BMI. By making the biking terrain less of an issue, people who wouldn't otherwise consider biking can use the electric assistance when needed and otherwise pedal as they are able. This means people of lower fitness levels or who haven't cycled in many years can start enjoying the many health benefits E-bikes have to offer.